Probiotic – original biological preparation for treating diarrhea and dysbacteriosis



Lyophilized bacterial cells from the specially selected strain Lactobacillus bulgaricus “I. Bogdanov patent strain tumoronecroticance B-51” ATCC #21815, shortly called “LB51®” in short. One gram of the preparation contains minimum 109 living bacterial cells.

Pharmacological properties

NORMOFLOR® is a preparation normalizing the intestinal flora. Orally applied NORMOFLOR® propagates in the intestinal tract and regains its productivity, acting antagonistically to pathogenic and conditional pathogenic enteric bacteria. The beneficial effects of the preparation is due to the suppression of the intestinal infections and stopping of the diarrhea syndrome, as well as to the quick regeneration of the intestinal mucuses, caused by the biologically active substances, synthesized by LB51®.


THERAPEUTIC – indigestion and diarrhea of bacterial origin (Salmonella, Shigella, Klebsiella, pathogenic Escherichia coli, Proteus, Pseudomonas); – dysbacteriosis resulting from wide spectrum antibiotic and/or sulfonamide treatment; – colitis – including ulcerative, haemorrhagic and radiation colitis and proctitis.

PROPHYLACTIC – during and after antibiotic and/or sulfonamide treatment for maintaining the normal intestinal flora and for prevention of dysbacteriosis.


In cases of acute diarrhea syndrome the treatment begins with 4 capsules of 250 mg and after that – 2 capsules on every 2 hours. During the following 3-4 days the treatment continues with 2 capsules 3-4 times a day, half an hour before meals. In cases with not so severely manifested symptoms – 2 capsules 3-4 times a day, half an hour before meals. In cases of intestinal disorders on neonates, breast fed children and infants, the contents of 1-2 capsules is dissolved in a small quantity of water or milk. This single dose is to be given 3-4 times a day depending on the severity of the symptoms. For stabilizing the achieved therapeutic effects the treatment should be continued for at least 5 days in doses 2-4 capsules a day. The treatment in cases with chronic colitis should go on for a longer period of time.


There are no counter-indications for the application of NORMOFLOR®.


There is no evidence for harmful influence of NORMOFLOR® during pregnancy or lactation.

Side effects

Side effects have not been observed.

Interaction with other pharmaceuticals

The activity of NORMOFLOR® decreases during application of antibiotics and/or sulfonamides, which requires increasing of the dosage of NORMOFLOR® and continuing its application after the termination of the antibiotic treatment.


Because of the absolute harmlessness of NORMOFLOR® the preparation could be applied even in greater doses depending on the severity of the illness and/or symptoms, which should be overcome. This gives the possibility to find the optimal dosage for every patient.


Vials containing 16 capsules of 250 mg each; PVC-aluminium blisters containing 10 capsules of 250 mg each.


Store in a dry airy place at a temperature from -20ºC to 18ºC. When stored for longer period of time it is recommended to store in refrigerator.

Expiry term

3 years.